A Brief Review of Multiple Sclerosis Treatments


1Parand Danafar, 2Mohammadmatin Nourikhani, 2Hasti Beigverdi, 3Mahan Fazel, 4Mohammad Mehdi Fazeli, 5Fatemeh Sadat Shariat Mostafavi, 5Amir Shakibaei, 5Leila Khalili, 6Samaneh Vafaei, 7Alex avakian, 8Mahdokht Yazdani Shokouh, 8 Seyed Ali Hosseini Zavareh,
1Department of Medicine, Islamic Azad University Kashan Branch, Kashan, Iran
2Medical Laboratory Science Student, Faculty of Allied Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
3D.V.M Student, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran
4Medical laboratory sciences student, Department of Laboratory Sciences, Chalus Branch, Islamic Azad university, Chalus, Iran
5Medical Student, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
6Molecular cell bachelor graduated, Department of Faculty of Modern Sciences and Technologies, Islamic Azad University Tehran Medical Siences,iran
7Department of Medicine, Islamic Azad University Sari branch,Sari, Iran
8Medical Student, Department of Medicine, Islamic Azad University Tehran Medical Sciences , Iran

Abstract

MS is a well-known disease and chronic inflammation in the central nervous system is one of the diseases whose etiology, despite its well-known autoimmune nature, is still debated, although according to recent studies, the role of viruses such as EBV approved. Based on the different phases that are defined for MS and the degree of progression of the disease, a specific protocol and treatment process is defined for the patient. New and safe treatments for autoimmune diseases have been a constant challenge, although side effects, albeit on a small scale and with few reports, are inevitable; In this study, we tried to classify based on how it is used on drugs used in the treatment of this disease, and at the same time the progress and achievement of new cases such as the use of monoclonal antibodies, despite all the progress made. We still do not fully meet the treatment needs of MS based on studies, in other words, in the classification system and review study, in the group of injectable drugs, we reviewed drugs such as Daclizumab, Alemtuzumab, Natalizumab, Copaxone and Mitoxanthron. Oral drugs Fingolimod, Teriflunomide, and Siponimod were also discussed. In addition to discussing MS medication, we reviewed other treatments such as the use of bone marrow stem cells that were previously discussed in preventing bone marrow suppression during severe therapies such as chemotherapy in the treatment of MS.

Keywords:

Multiple Sclerosis, MS Treatments

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